Functional composite coatings consisting of nano- and micro- filler particles are suitable candidates to meet the property and performance requirements in applications ranging from aerospace to biomedical implants. We design and synthesize functional composite surfaces with specific surface properties and functionalities like anti-icing, anti-corrosive and anti-microbial surfaces. The functionality is based upon the release of active agents from the functional composite surfaces. Functional surfaces are synthesized by using spin coating, dip coating, drop-casting and layer-by-layer deposition techniques.
Self-Organization of Polymers
Stimuli-responsive polymeric materials are capable of changing their physical behaviour with external stimuli in the environment. The understanding and tailoring of the properties of self-assembled structures built by stimuli-responsive polymers are important in biomedical applications. We investigate the formation and controlled release applications of hydrogen-bonded self-assembled structures of thermoresponsive polymer and pH-responsive molecules.
Drugs with low aqueous solubility and good permeability have dissolution-related bioavailability problems. The preparation of solid dispersion is one of the prominent methods to enhance solubility, dissolution rate and thus, the bioavailability of poorly soluble drugs.